ENNext Generation Digital Learning Environment (NGDLE) was established according H2020 project “Up to University” (Up2U). In order to increase and promote application of NGDLE in Lithuanian schools a set of strategies were used during particular stages of the project and piloting of the platform was combined with teachers’ Continuing Professional Development (CPD). In this paper we present developed infrastructure, discuss key success factors and analyse survey data collected from teachers and students during large-scale piloting in Lithuania.