ENThe article introduces to one of the largest old Vilnius Cyrillic scripts collection (130 items) which is preserved now at Vernadsky National Library of Ukraine. Majority of these Cyrillic books to the National Library were brought from various monasteries of Ukraine. 16th–19th c. publications of Vilnius printers are being analysed considering various aspects of book science: versions of text printing, artful typography, and especially watermark designs. A research about Cyrillic scripts’ paper helps to reinstate the printers’ work schedule. Moreover, it is important to study Vilnius Cyrillic scripts provenances as they disclose peculiarities of East Slavic spiritual and cultural connections.