ENThe purpose of this research is to present a conceptual model of Port Organizational Ecosystem (POE) resilience and to develop a framework of managerial interventions to enhance POE resilience in the conditions of high uncertainties. Utilizing a mixed-methods approach, data were collected through focus group interviews and analysed using thematic and statistical methods. The analysis identified key challenges, including global supply chain disruptions, technological advancements, and governance-related issues, emphasizing the critical role of adaptable governance frameworks in mitigating these challenges. Findings reveal that while technological innovations pose challenges, they also offer tools to enhance operational sustainability and resilience. The research highlights managerial weaknesses that complicate these challenges, underscoring the need for managerial interventions focusing on engagement, diversification, and compliance. Research implications suggest the necessity for adaptive leadership and governance structures that promote inclusivity and strategic foresight. Practically, this paper outlines a framework of managerial interventions for improving POE resilience, offering valuable insights for port authorities to integrate worldwide best practices into their operations. This study contributes original insights by linking governance patterns with resilience enhancement, providing a structured approach to understanding and improving POE resilience in the global maritime landscape. Keywords: entrepreneurship, managerial interventions, port organizational ecosystem, port resilience, port governance.