ENThe global COVID-19 pandemic has affected both health system and economy. This impact is being felt around the world, but the challenges of the coronavirus management affect communities very differently. The quarantine, self-isolation, restriction of social contacts, changes in the organization of work and study, etc. introduced for pandemic management affect each person in a very different way. More and more research findings demonstrate that stress experienced affects psychological well-being and even mental health. This article discusses the results of a study of psychological well-being conducted in one academic community during the second quarantine. Key words: psychological well-being, pandemic, quarantine, coronavirus, material conditions, social factors.