ENThe chapter analyses practical issues regarding the economic specificity of US foreign direct investments (FDI) to selected EU countries. Therefore, four countries were selected the United Kingdom, Germany, Belgium and Lithuania. There are plenty of tariff and non-tariff barriers to successful trade relations between the EU and the USA. The aim is to define the specificity of economic aspects of US FDI to selected EU Member States. The first task was, to analyze the legal basis of agreements that affect exports from the USA to the EU. The second task—to provide a comprehensive economic analysis of the main investment trends from the USA to selected EU Member States. The analysis starts with a description of the investment environment and continues with a presentation of the US outward FDI stock to the selected EU countries. The research methods used are a systematic overview of the history of investment relations between the EU and the USA, and a descriptive method presenting the current investment situation between the EU and the USA, its challenges, issues and trends. Keywords: Foreign direct investments (FDI); USA; European Union; TTIP; EU-USA investment trends; Lithuania. [Publisher annotation]